Benign epithelial melanosis of the conjunctiva
Mar 1, 2013 · Definition / general. Pigmented thickening of conjunctival epithelium, may be normal finding in dark skinned individuals - bilateral, continues throughout life (Surv Ophthalmol 2004;49:3) Present in 92% of blacks, 36% of Asians, 28% of Hispanics, 5% of whites. Uncommon finding in Laugier-Hunziker syndrome (Arch Dermatol 2007;143:631)
Pathology Outlines - Blue nevus / cellular blue nevus
Jan 23, 2023 · Congenital dermal melanocytosis: Formerly known as Mongolian spot. Benign fibrous histiocytoma: Hemosiderin pigment, no melanin Dermatofibrosarcoma protuberans: More cellular, tight storiform pattern, infiltrative, has pigmented variant Nevus of Ito / nevus of Ota; Desmoplastic nevus (Arch Pathol Lab Med 2011;135:327) Desmoplastic Spitz nevus
Pathology Outlines - Congenital nevus
Sep 15, 2022 · Essential features. Nevi that are present at birth or shortly thereafter (StatPearls: Congenital Melanocytic Nevi [Accessed 15 September 2022]) Characterized by bland melanocytic proliferation in the dermis; melanocytes prominently cluster around dermal appendages and show maturation in the depth. Excellent prognosis.
Pathology Outlines - Melanosis coli
Feb 1, 2021 · 40 year old woman with colonic lymphoid hyperplasia in melanosis coli (Arch Pathol Lab Med 2001;125:1110) ...
Atypical melanocytic nevi of the genital type-vulva
Dec 18, 2023 · The histologic features are consistent with atypical melanocytic nevi of genital type (AMNGT). Although HMB45 expression varies in nevi, the stain can be useful to highlight the maturation (zonation) pattern (diminished or loss of expression from epidermal to dermal component). Answers A, C and D are incorrect because PRAME is usually diffusely ...
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Jun 13, 2024 · HMB45, (human melanoma black) developed in 1986 from an extract of melanoma cells, is a monoclonal antibody that targets the premelanosome protein gp100
Pathology Outlines - Eye
Uvea (iris, choroid and ciliary body), limbus and sclera: ciliary body adenoma and adenocarcinoma Lisch nodule medulloepithelioma melanoma-uvea ocular melanocytosis nevi-choroid or iris primary choroidal lymphoma (pending) uveitis. Eye stains: PASD Disorders from other chapters basal cell carcinoma sebaceous cell carcinoma Other hematolymphoid ...
WHO classification of tumors of the conjunctiva and caruncle
Aug 12, 2024 · It is the most common melanocytic lesion of the conjunctiva. This is a conjunctival compound nevus, which is the most common melanocytic lesion of the conjunctiva. They are benign. Differentials include primary acquired melanosis, racial melanosis, ocular melanocytosis and malignant melanoma.